Symptomatic and nonamyloid/tau based pharmacologic treatment for Alzheimer disease.
نویسندگان
چکیده
In this work we consider marketed drugs for Alzheimer disease (AD) including acetylcholinesterase inhibitors (AChE-Is) and antiglutamatergic treatment involving the N-methyl-d-aspartate (NMDA) receptor. We discuss medications and substances available for use as cognitive enhancers that are not approved for AD or cognitive impairment, and other neurotransmitter-related therapies in development or currently being researched. We also review putative therapies that aim to slow disease progression by mechanisms not directly related to amyloid or tau.
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ورودعنوان ژورنال:
- Cold Spring Harbor perspectives in medicine
دوره 2 3 شماره
صفحات -
تاریخ انتشار 2012